Derivatives of 3'- and 3"-O-desmethyl avermectin compounds, comp

Details Derivatives of 3'- and 3"-O-desmethyl avermectin compounds, comp Derivatives of 3'- and 3"-O-desmethyl avermectin compounds, comp

1990-05-11

1992-12-08

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3170, C07H 1704

Patent

active

051698390

ABSTRACT:
There are disclosed derivatives of avermectin compounds wherein one or both of the 13-oleandrose saccharide groups lack the methyl group of the 3'- or 3"-methoxy. Such compounds are potent anthelmintic and antiparasitic agents.

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patent: 4289760 (1981-09-01), Mrozik et al.
patent: 4427663 (1984-01-01), Mrozik
patent: 4997383 (1990-01-01), Sinclair
Schulman et al (I), The Journal of Antibiotics 38, pp. 1494-1498 (1988).
Schulman et al (II), Antimicrobial Agents and Chemotherapy, pp. 744-747 (1987).

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