Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[.

Details Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[. Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[.

1975-10-30

1976-11-30

Coughland, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260286R, 260287CF, 260288D, C07D21722

Patent

active

039950417

ABSTRACT:
2-Substituted-hydroxyanilino-hexahydro-2H-benzo[.alpha.]quinolizines of the structural formula, ##SPC1##
In which R.sup.1 is a hydrogen atom or an alkanoyl group of 2 to 4 carbon atoms and each of substituents R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 is a hydrogen atom, a hydroxyl, or a methyl group, such that at least one of the latter substituents is a hydroxyl group, exhibit coronary vasodilating activity.

REFERENCES:
patent: 3634431 (1972-01-01), Van Dyke
patent: 3635986 (1972-01-01), Van Dyke
Van Dyke et al., J. Med. Chem., vol. 15, (1972) pp. 91-94.

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