Derivatives of [[(1-piperidinyl)ethyl]phenyl]alkanediamines

Details Derivatives of [[(1-piperidinyl)ethyl]phenyl]alkanediamines Derivatives of [[(1-piperidinyl)ethyl]phenyl]alkanediamines

1975-05-08

1976-10-05

Milestone, Norma S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029373, C07D29512

Patent

active

039844218

ABSTRACT:
Compounds of the formula ##SPC1##
And pharmaceutically acceptable salts alkylthio, wherein R.sub.1 is hydrogen, halogen, alkyl, alkoxy, alkythio, benzyl, phenylethyl, phenyl, phenylthio, or phenyl mono-substituted with a halogen, an alkyl group, an alkoxy group or a trifluoromethyl group; R.sub.2 is hydrogen, Halogen, alkyl, alkoxy, alkylthio, alkylsulfonyl, phenyl phenyloxy, sulfamoyl, dialkylamidosulfonyl, trifluoromethyl or phenyl or phenyloxy mono-substituted with a halogen, an alkyl group, an alkoxy group or a trifluoromethyl group; R.sub.3 is hydrogen, alkyl or or hydroxyalkyl; and n is 2, 3 or 4 are useful as central nervous system depressants.

REFERENCES:
patent: 2626948 (1953-01-01), Finkelstein et al.
patent: 3536712 (1970-10-01), Keck et al.
Kindler et al., e.a. 45:1970 g (1951).

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