Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as...

Details Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as... Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as...

2011-04-12

2011-04-12

Andres, Janet L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S345000

Reexamination Certificate

active

07923565

ABSTRACT:
Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.

REFERENCES:
patent: 7671066 (2010-03-01), Amari et al.
patent: 2006/0239927 (2006-10-01), Ohshima et al.
patent: 2008/0015226 (2008-01-01), Amari et al.
Ducharme et. al., “Substituted 2-pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors”, Bioorganic & Medicinal Chemistry Letters 2003, 13 (11), pp. 1923-1926.
Patani et. al., “Bioiosterism: A Rational Approach in Drug Design”, Chem. Rev. 1996, 96, pp. 3147-3176.
Darrow, Jonathan, “The Patentability of Enantiomers: Implications for the Pharmaceutical Industry”, 2007 Stan. Tech. L. Rev. 2, Feb. 27, 2007.
U.S. Appl. No. 12/700,926, filed Feb. 5, 2010, Amari, et al.

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