Derivatives of 1-diphenylmethyl piperazine and their use as anti

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544231, 544366, 544370, 544371, 544372, 544396, A61K 31495, C07D40304

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active

051662051

ABSTRACT:
The present invention relates to novel derivatives of 1-diphenylmethyl piperazinyl, characterized in that they correspond to the general formula I, and their therapeutically acceptable salts, ##STR1## in which: R.sub.1 and R.sub.2, equal or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxy radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical,

REFERENCES:
patent: 3491098 (1970-01-01), Archer
patent: 3631043 (1971-12-01), Regnier et al.
patent: 4338453 (1982-07-01), Gall
patent: 4377578 (1983-03-01), Vandenberk et al.
patent: 4525358 (1985-06-01), Baltes et al.
patent: 4908365 (1990-03-01), Buzas et al.
patent: 5043447 (1991-08-01), Pascal et al.
Gubert et al., "Synthesis of some N-benzhydrylpiperazine drivatives as calcium antagonists," Arzneimittel Forchung, 37(10):1103-1107 (1987).
Boti, J. A. et al., Chemical Abstracts 106(3):614 (1987), Abstract Number 18620u.
Gomez et al., Chemical Abstracts 107(1):668 (1987), Abstract Number 7214j.
Alcaloides, Chemical Abstracts 108(15):763 (1988), Abstract Number 131862d.
Kon et al., Chemical Abstracts 113(17):767 (1990), Abstract Number 152278m.
Hazato et al., Chemical Abstracts, vol. 114, No. 142900 (1991)(Abstract for WO 90 12001 Oct. 18, 1990).
Morren et al., Bull. Soc. Chim. Belg. 60, p. 282 (1951).
de Meglio et al., Farmaco, Ed. Sci., 42, pp. 359-382 (1987).
Baltzly et al., J. Org. Chem. 14, p. 775 (1949).

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