Derivatives of 1-arylsulphonyl-2-oxo-5-alkoxy-pyrrolidine and me

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548542, C07D20738, A61K 3140

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active

048853062

ABSTRACT:
Compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures, senescence or mental strain of the formula (I) ##STR1## in which R' and R.sub.2, being identical or different, represent hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, alkenyl containing from 2 to 8 carbon atoms, acyl containing from 1 to 6 carbon atoms or aralkyl containing from 7 to 15 carbon atoms, R.sub.1 represents a possibly substituted aryl containing up to 14 carbon atoms, or a possibly substituted mono- or polycyclic heterocyclic aromatic radical; also therapeutic compositions containing those compounds and method of use.

REFERENCES:
patent: 3117975 (1964-01-01), Bortnick et al.
patent: 3423426 (1969-01-01), Kohn
patent: 3686169 (1972-08-01), Coran et al.
Drugs of the Future, vol. 10, No. 12, 1985, pp. 972, 974.

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