Derivatives of 1-arylsulphonyl-1,5-dihydro-2H-pyrrol-2-one, and

Details Derivatives of 1-arylsulphonyl-1,5-dihydro-2H-pyrrol-2-one, and Derivatives of 1-arylsulphonyl-1,5-dihydro-2H-pyrrol-2-one, and

1988-06-13

1989-12-05

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548542, C07D20738, D61K 3140

Patent

active

048853070

ABSTRACT:
Compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures, senescence or mental strain of the formula (I) ##STR1## in which R' represents hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, alkenyl containing from 2 to 8 carbon atoms, acyl containing from 1 to 6 carbon atoms or aralkyl containing from 7 to 15 carbon atoms and R represents aryl containing up to 14 carbon atoms, possibly substituted, or a mono- or polycyclic heterocyclic aromatic radical, possibly substituted; also thereapeutic compositions containing those compounds and method of use.

REFERENCES:
patent: 3117975 (1964-01-01), Bortnick et al.
patent: 3423426 (1969-01-01), Kohn
patent: 3686169 (1972-08-01), Coran et al.
Drugs of the Future, vol. 10, No. 12, 1985, pp. 972, 974.

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