Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid

Details Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid

1994-11-09

1996-08-13

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514300, 546123, 546156, A61K 3147, C07D21520

Patent

active

055456421

ABSTRACT:
The invention relates to novel derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid which are substituted in the 7 position by a 2,3,4,5,6,7-hexahydro-1H-pyrrolo[3,4-c]pyridin-2-yl or 1,2,3,4,5,6-hexahydropyrrolo[3,4-c]pyrrol-2-yl residue, to their salts, to a process for their preparation and to antibacterial agents containing these derivatives.

REFERENCES:
patent: 5091384 (1992-02-01), Kim et al.
patent: 5274167 (1993-12-01), Lange et al.
patent: 5312823 (1994-05-01), Petersen et al.
Atarashi, S. Imamura M. Kimura Y. Yoshida A. Hayakawa I. J. Med Chem., vol. 36, pp. 3444-3448 (1993).

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