Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Details Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

1989-07-31

1991-03-12

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514879, C07D21910, A01N 4342

Patent

active

049994301

ABSTRACT:
Novel prodrugs or depot derivatives of 1,2,3,4-tetrahydro-9-acridinamine are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.

REFERENCES:
Stewart, J., J. Pharm. Sci., 1973, 62(8), to 1357-8.
Stewart et al., J. Med. Chem, 1970, 13(4), 762.
Chemical Abstracts, p. 80, 110:128660x.

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