Derivative of kojic acid and its use as a depigmenting agent

Drug – bio-affecting and body treating compositions – Bleach for live hair or skin

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424 43, 424450, 424489, 424DIG5, 514365, 514844, 514846, 514937, 514944, 514945, 548201, A61K 748

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059684879

ABSTRACT:
The invention relates to a novel derivative of kojic acid of formula (I) and to its use, in a composition for topical application as a depigmenting and/or bleaching agent for skin: ##STR1## The invention also relates to a process for depigmenting and/or bleaching skin, which includes applying to the skin a composition that contains 5-hydroxy-4-oxo-4H-pyran-2-ylmethyl 2-oxothiazolidine-4-carboxylate of formula (I) or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 5208249 (1993-05-01), Rowe et al.
Chemical Abstracts, vol. 121, No. 10, Sep. 5, 1994, pp. 589 & JP 06 133 773 A (abstract only).

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