Derivative of .alpha., .alpha.-trehalose and a process for prepa

Details Derivative of .alpha., .alpha.-trehalose and a process for prepa Derivative of .alpha., .alpha.-trehalose and a process for prepa

1986-12-08

1989-03-21

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536117, 536119, C07H 1302, A61K 31715

Patent

active

048144363

ABSTRACT:
Derivatives of .alpha.,.alpha.-trehalose-6,6'-fatty acid diester having phosphoric ester groups in the molecule which are useful as a carcinostatic agent. One of the derivatives may be prepared by reacting diphenylphosphoryl chloridate with a derivative of 2,3,2',3'-tetra-O-benzyl-.alpha.,.alpha.-trehalose-6,6'-fatty acid diester. Another derivative may be obtained by substituting benzyl groups at 2,3,2',3' positions of trehalose with hydrogen atoms.

REFERENCES:
patent: 4612304 (1986-09-01), Fukushi
patent: 4684719 (1987-08-01), Nishikawa et al.
patent: 4720456 (1988-01-01), Wagner et al.

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