Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1980-10-06
1982-02-16
Rosen, Sam
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
424101, A61K 3514, A61K 3700
Patent
active
043159192
ABSTRACT:
Biological and pharmaceutical products which are contaminated with pyrogens are depyrogenated by prolonged contact with a solution or suspension of from about 0.25% to about 10% by weight of a non-denaturing amphiphile.
REFERENCES:
Mochida et al.-Chem. Abst. vol. 76, (1972) p. 21481s.
E. Work, "Production, Chemistry and Properties of Bacterial Pyrogens and Endotoxins" in Pyrogens and Fever, Ciba Foundation Symposium, 1971, pp. 23-47, Churchill Livingstone.
Chemical Abstracts, vol. 85, 190481h, 1976.
Rosen Sam
Schellin Eric P.
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