Depth-resolved fluorescence instrument with angled excitation

Optics: measuring and testing – By dispersed light spectroscopy – With sample excitation

Reexamination Certificate

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C250S458100, C600S317000

Reexamination Certificate

active

10986605

ABSTRACT:
A fluorescence instrument illuminates the surface of tissue with light of a selected wavelength and light emanating from the tissue due to fluorescence is collected. The angle of illumination of tissue surface and/or collection of fluorescence is changed to probe at various depths beneath the surface of the tissue for a fluorescence layer. Three embodiments of the instrument are described.

REFERENCES:
patent: 6014204 (2000-01-01), Prahl et al.
patent: 6423956 (2002-07-01), Mandella et al.
patent: 2002/0080357 (2002-06-01), Dana
patent: 2005/0148834 (2005-07-01), Hull et al.

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