Depsipeptide compound

Details Depsipeptide compound Depsipeptide compound

2006-08-29

2006-08-29

Kam, Chih-Min (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C514S009100, C514S010100, C530S317000, C530S330000

Reexamination Certificate

active

07098024

ABSTRACT:
This invention relates to a novel compound which has a cytotoxic activity and TGF-β like activity for human cancer cells and is useful as an antitumor agent and to a pharmaceutical composition which contains the same.

REFERENCES:
patent: 5849540 (1998-12-01), Baz et al.
patent: 0 352 646 (1990-01-01), None
patent: 61-101501 (1986-05-01), None
patent: WO 95/27730 (1995-10-01), None
XP-000978243—T. H. Nielsen et al., “Viscosinamide, a new cyclic depsipeptide with surfactant and antifungal properties produced by Pseudomonas fluorescens DR54”, Journal of Applied Microbiology, vol. 86, No. 1 (1999), pp. 80-90.
XP-004227786—Y. Masuoka et al., “Spiruchostatins A and B, novel gene expression-enhancing substances produced by Pseudomonas sp.”, Tetrahedron Letters (2001) vol. 42, No. 1, pp. 41-44.
European Search Report dated Apr. 5, 2004.

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