Deoxyaminoglycoside antibiotic derivatives

Details Deoxyaminoglycoside antibiotic derivatives Deoxyaminoglycoside antibiotic derivatives

1974-07-10

1977-12-27

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 12, 536 17, C07H 1522

Patent

active

040656152

ABSTRACT:
A new deoxystreptamine-containing aminoglycoside antibiotic derivative in which all the amino groups other than the amino group at the 1-position of the deoxystreptamine moiety are formylated is obtained in a high yield by treating a deoxystreptamine-containing aminoglycoside antibiotic derivative in which all the amino groups are formylated with a basic substance. The new derivatives are very important for production of 1-N-modified deoxystreptamine-containing aminoglycoside antibiotics.

REFERENCES:
patent: 3678030 (1972-07-01), Yamazaki et al.
patent: 3826802 (1974-07-01), Kawaguchi et al.
patent: 3923783 (1975-12-01), Naito et al.
patent: 3925354 (1975-12-01), Umezawa et al.
patent: 3932382 (1976-01-01), Ohki et al.
patent: 3960833 (1976-06-01), Naito et al.
Umezawa et al., "The Jour. of Antibiotics," vol. XXV, No. 10, 1972, pp. 613-615.

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