Deoxy and oxygen-substituted sugar-containing 14-aminosteroid co

Details Deoxy and oxygen-substituted sugar-containing 14-aminosteroid co Deoxy and oxygen-substituted sugar-containing 14-aminosteroid co

1995-06-02

1998-02-24

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514182, 514821, 514824, 536 5, 536 185, A61K 31705, C07H 1524

Patent

active

057212171

ABSTRACT:
Disclosed are 14-aminosteroid compounds, including pharmaceutically acceptable acid salts and esters thereof, useful in treating individuals afflicted with congestive heart failure, which compounds have the general formula: ##STR1## wherein R.sub.3 is a deoxy or oxygen-substituted monosaccharide sugar residue and R.sub.1, R.sub.2 and R.sub.4 are various other substituents as defined herein.

REFERENCES:
patent: 4552868 (1985-11-01), Jarreau et al.
patent: 4584289 (1986-04-01), Jarreau et al.
patent: 4885280 (1989-12-01), Jarreau et al.

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