Dentifrice compositions

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 57, A61K 716, A61K 718

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active

050967029

ABSTRACT:
The present invention relates to a dentifrice composition having an improved anti-plaque effect. The composition comprises stanous pyrophosphate as an anti-plaque agent, the activity of which can be increased according to the invention by including a water-soluble monofluorophosphate salt in the composition.

REFERENCES:
patent: 3984814 (1976-11-01), Cordon
patent: 4335102 (1982-06-01), Nakashima et al.
patent: 4348378 (1982-09-01), Kosti
patent: 4363794 (1982-12-01), Ochal et al.
patent: 4459277 (1984-07-01), Kosti
patent: 4522806 (1985-06-01), Muhlemann et al.
patent: 4585648 (1986-04-01), Maeyama et al.
patent: 4702904 (1987-10-01), Maeyama et al.
patent: 4970064 (1990-11-01), Adam et al.
Nakashima et al, C.A.95:192230f (1981) 1 PR. 2462160 Feb. 13, 1981.
Lion Corp. CA.95:156375y (1981) of JP 56075422 Jun. 22, 1981.
Svatun, B. "Plaque-inhibiting efffect of dentifrices containing stannous fluoride", (1978) pp. 205-210.
Svatun & Rolla, "The Role of Stannous Pyrophosphate in the plaque-inhibiting effect of dentifrices containing stannous fluoride",`Tooth surface interactions & preventive dentistry` (1981) pp. 33-37.
English Translation of Japanese Patent 56/45408 (Lion).

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