Dentifrice

Details Dentifrice Dentifrice

1976-10-29

1978-04-04

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ferment containing

424 52, A61K 718, A61K 728

Patent

active

040828417

ABSTRACT:
There is disclosed in this specification an improved composition for reducing dental plaque and calculus formation, comprising zinc ions and an organoleptically acceptable enzyme, which may be a protease, carbohydrase, or lipase, or mixtures of these enzymes.

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McConn, et al., J. Biol. Chem., vol. 239, pp. 3706-3715, Nov. 1964, Bacillus Subtilis Neutral Proteinase, a Zinc Enzyme of High Specific Activity.
Parisi, et al., Amer. J. Clin. Nutr., vol. 22, pp. 1222-1239, Sept. 1969, "Zinc Metalloenzymes: Characteristics and Significance in Biology and Medicine."
Molle, J. S. Cal. State Dent. Assoc., 35: 391-393, Sept. 1967, Efficacy of an Enzyme Tooth Paste in the Retardation of Dental Plaque.
Chem. Abstr., 78 #115218e (1973), of South Africa, 7,100,701, Aug. 4, 1972, Pador, M. Chem. Abstr. 78 #75857d (1973), of Brit. 1,296,952, Nov. 22, 1972.

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