Dental therapy by vesicle delivery

Details Dental therapy by vesicle delivery Dental therapy by vesicle delivery

1986-06-24

1988-08-30

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Dentifrices

Phosphate compound containing

424 49, 424 54, A61K 716

Patent

active

047676159

ABSTRACT:
A known procedure is used to prepare liposomes of bipolar lipid membrane which are permeable and hence "leak" their contents at a rate which is variable by choice. The liposome is supplied with medication or cosmetic material for the oral cavity, or specifically for the teeth and gums. The liposome is then attached to a molecule that has affinity for the hydroxyapatite. Thus, the liposome will bind to oral cavity hydroxyapatite and bathe the surrounding support surface with its contents for extended hours of service.

REFERENCES:
patent: 4483929 (1984-11-01), Szaka
patent: 4603044 (1986-07-01), Geho
Accepted Dental Therapeutics, 38th Ed., American Dental Association, Chicago, Ill. 1979, p. 343.
Jones et al. in Chemical Week, McGraw-Hill Inc., Jul. 30, 1986, pp. 426-5129, "Liposome Research: New Path for Drug Delivery".

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