Dental products to treat and prevent periodontal disease

Details Dental products to treat and prevent periodontal disease Dental products to treat and prevent periodontal disease

1997-08-18

1999-05-04

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

424 48, 424435, 424440, 424 52, A61K 716, A61K 718, A61K 968, A61K 920

Patent

active

059002301

ABSTRACT:
The dental products of this invention can be used to treat and prevent periodontal disease. They contain a synergistic mixture of poloxamers, and/or poloxamer congeners, plus xylitol. These active ingredients are present in specific amounts. It is also necessary to eliminate all irritants from the dental products of this invention. The dental products of this invention include a dentifrice paste or gel, powder, granules, disintegrable tablet, and a mouthwash, lozenge, and chewing gum.

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H. Bleeg, "Nonspecific Cleavage of Collagen by Proteinases in the Presence of Sodium Dodecyl Sulfate," Scand. J. Dent. Res., 98,235-241 (1990).
B. Herlofson, P. Barkvoll, "Sodium Lauryl Sulfate and Recurrent Aphthous Ulcers (a preliminary study)," Acta Odontol. Scand., 52, 257-259 (1994). (Teaches to Avoid Sodium Lauryl Sulfate to Aviod Recurrent Aphthous Ulcers).

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