Drug – bio-affecting and body treating compositions – Chewing gum type
Patent
1983-06-06
1986-02-04
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Chewing gum type
426 3, 426 5, A61K 968
Patent
active
045685371
ABSTRACT:
A method for promoting dental health in which chewing gum is employed to alter the oral environment to provide natural resistance to dental caries. The method involves chewing a sugarless gum which contains a relatively insoluble, hydrophobic food-grade organic acid, preferably adipic acid. Chewing of the gum gradually releases the acid from the gum at a desirably linear rate over a period of approximately 20 to 30 minutes. Release of the acid from the gum into the mouth stimulates an increase in salivary flow rate greater than that experienced during chewing a non-acidulated chewing gum, resulting in increases in salivary electrolytes and basic proteins and in the concentration of natural salivary bicarbonate to a level in excess of that necessary to neutralize the acidulant being released from the gum. The excess of natural salivary bicarbonate raises the salivary pH and plaque pH and neutralizes microbially-formed lactic acid responsible for tooth demineralization and resultant dental caries.
REFERENCES:
patent: 1630763 (1927-05-01), Raymer et al.
patent: 2812256 (1957-11-01), Nerfin
patent: 3632358 (1972-01-01), Echeandra et al.
patent: 4064274 (1977-12-01), Mackay et al.
patent: 4065578 (1977-12-01), Reggio et al.
patent: 4085227 (1978-04-01), Mackay et al.
patent: 4088788 (1978-05-01), Ream et al.
patent: 4134999 (1979-01-01), Muhler et al.
patent: 4151270 (1979-04-01), Ream et al.
patent: 4208431 (1980-06-01), Friello et al.
patent: 4217368 (1980-08-01), Witzel et al.
patent: 4248895 (1981-02-01), Stroz et al.
patent: 4250196 (1981-02-01), Friello et al.
patent: 4252830 (1981-02-01), Kehoe et al.
patent: 4271197 (1981-06-01), Hopkins et al.
patent: 4271199 (1981-06-01), Cherukuri et al.
patent: 4301178 (1981-11-01), Witzel et al.
patent: 4316915 (1982-02-01), Friello et al.
patent: 4317837 (1982-03-01), Kehoe et al.
patent: 4328249 (1982-05-01), Mackay et al.
patent: 4352825 (1982-10-01), Cherukuri et al.
patent: 4352853 (1982-10-01), Cherukuri et al.
patent: 4357354 (1982-11-01), Kehoe et al.
patent: 4399154 (1983-08-01), Puglia
patent: 4400372 (1983-08-01), Muhler et al.
Kleber, J. et al., "Changes in Salivary pH After Ingestion of Sorbitol Tablets Containing Various Food Acidulatns", J Dent Res, vol. 58 (6) pp. 1564-1565 (Jun. 1979).
G. N. Jenkins, "Salivary Effects on Plaque pH" (In Saliva and Dental Caries, Eds. Kleinberg, I., Ellison, S., and Mandel, I., Sp. Supp. Microbiology Abstracts, p. 307 (1979)).
Hoerman Kirk C.
Nevin Charles S.
Rose Shep K.
Wm. Wrigley Jr. Company
LandOfFree
Dental health method employing chewing gum does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dental health method employing chewing gum, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dental health method employing chewing gum will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2339837