Dentistry – Method or material for testing – treating – restoring – or...
Patent
1989-06-28
1992-05-05
Millin, V.
Dentistry
Method or material for testing, treating, restoring, or...
4332171, A61C 500
Patent
active
051107201
DESCRIPTION:
BRIEF SUMMARY
The invention relates to a new dental composition and to a process for the preparation thereof.
As known, caries is the most widespread endemic disease. It is quite obvious to one skilled in the art that a great deal of teeth could be saved by a preservative treatment performed in due time. In practice, however, patients turn to the dentist only when they suffer from an untolerable pain, i.e. when at least one complication exists, too.
Pain is caused first by pulp hyperaemia, i.e. by the reversible inflammation of the vessels and intravascular nerves of the dental radix. The volume of the narrow pulp canal, closed between hard walls, cannot increase, thus the arteries exert a hard pressure on the veins, which results in an early appearance of venal hyperaemia. At the stage of pulp hyperaemia, however, caries does not reach the pulp, since it is separated from it by a thin healthy layer of dentin.
When caries proceeds, an infectious inflammation appears in the pulp (pulpitis). Of the various forms of pulpitis only the main types are mentioned now. When an acute inflammation exists and the pulp is only partially damaged, dentists endeavour to save the living tooth. When inflammation gets, however, cronic and the pulp is completely damaged, the goal of dental treatment is to render the further treatment painless, to exclude additional complications and to ensure a symptom-free recovery.
In its final stage, pulpitis leads to gangrene. Tooth necrosis does not terminate, however, in the pulp. The defensive mechanism of the organism can act against infections only at territories with good blood supply. Periodontium, which surrounds the tooth, suits this requirement, consequently the next stage is the appearance of periodontitis. At the appearance of this disorder, causing pains even upon touch, pulp itself is no longer sensitive, the subjective symptoms are, however, very painful. The task of dentists is to ensure the quick alleviation of this complaint in the acute stage of inflammation. In chronic stages, however, additional complications must be taken into account. Inflammation may spread over the periodontal bony substance where it may lead to pathologic osteoporoses (granuloma, cysts).
Several attempts have been made to defend the exacerbation of the above diseases. According to Adler and Zaray [Konzervalo fogaszat (Preservative Dentistry) p. 172 (Medicina, Budapest, 1972) (in Hungarian)] pulp canal must be sterilized completely. It is very important that the surrounding tissues be free of inflammation. Therefore pulp canal has been treated with various sterilizing agents, antibiotics and antiphlogistics, utilized most frequently as a liquid composition. A disadvantage of this method is that prolonged activity cannot be ensured.
Utilization of powders or removable pastes in such treatments has also been attemped [Fogorvosi Szemle (Dentists' Review) 64, 404 (1971) (in Hungarian)], but prolonged effect could not be achieved.
Hungarian patent No. 167,308 suggests the use of pointers comprising a sterilizing (i.e. oxidizing) or antiphlogistic agent and/or an antibiotic in admixture with an inert plastic carrier. Penicillin, chloramphenicol and oxytetracyclin are mentioned as antibiotics, whereas hydrocortisone is mentioned as antiphlogistic agent. The major disadvantage of this method is that it can be applied only for the treatment of excavated pulp canal, furthermore it cannot act against osteoporosis coupled with other complications.
The invention aims at providing a new composition applicable for the treatment of caries and for the healing of acute, subacute or chronic inflammatory lesions of pulp, dental radix or the bony substance surrounding them.
Our extensive experimental work has led to the unexpected recognition that a particular combination, i.e. a combination of ipriflavone (7-isopropoxy-isoflavone) and an antiphlogistic agent can be utilized with good results for the complex treatment of teeth. Depending on the conditions of use, this combination can be supplemented with chemotherapeutic agents, lo
REFERENCES:
patent: 3913229 (1975-10-01), Driskell et al.
patent: 4121940 (1978-10-01), Michel et al.
Balogh Tibor
Csanyi Endre
Csanyi Gabor
Nagy Laszlo
Millin V.
Reanal Einomvegyszergyar
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