Dental caries inhibiting product of immunized cow's milk having

Details Dental caries inhibiting product of immunized cow's milk having Dental caries inhibiting product of immunized cow's milk having

1977-03-10

1982-04-13

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3909

Patent

active

043247822

ABSTRACT:
The use of a milk product containing antibodies to Streptococcus mutans for ingestion through the oral cavity and/or application to teeth to inhibit or reduce the incidence of dental caries, and the product itself.

REFERENCES:
patent: 3128230 (1964-04-01), Heinbach
patent: 3376198 (1968-04-01), Petersen et al.
Berkenbilt et al., J.A.D.A. vol. 83: 332-337, Aug. 1971, Development of Antibodies to Cariogenic Streptococci in Children.
Olson et al., Chem. Abstracts vol. 77 #36969 (1972) of Infer. Immunity S(4):419-427 (1972) Adherence Inhibition of Streptococcus mutans. Assay Reflecting a Possible Role of Antibodies in Dental Caries Prophylaxis, Exhibit "A".
Bowen, British Dental Journal: 159-160, Feb. 18, 1969, A Vaccine Against Dental Caries (Exhibit C).
Taubman (1973), Symposium on Comparative Immunology of the Oral Cavity, Phila., Pa. (1971) DHEW Pub. No. NIH73-438: 138-158, "Role of Immunization in Dental Disease".
McGhee et al., Immunochemistry 12: 817-823 (1975) Rat Immunoglobulins in Serum and Secretions: Purification of Rat IgM, IgA and IgG and their Quantitation in Serum, Colostrum, Milk and Saliva.
McGhee et al., J. Immunology 114 No. 1 Part Z: 303-305, Jan. 1975, Effective Immunity to Dental Caries: Protection of Gnotobiotic Rats by Local Immunization with Streptococcus mutans.
Michalek et al., Science 192:1238-1240, Jun. 18, 1976, Ingestion of Streptococcus mutans Induces Secretory Immunoglobulin A and Caries Immunity.

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