Dendritic chemiluminescent substrates

Details Dendritic chemiluminescent substrates Dendritic chemiluminescent substrates

2011-02-08

2011-02-08

Haq, Shafiqul (Department: 1641)

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

C436S172000, C436S528000, C436S531000, C436S805000

Reexamination Certificate

active

07883903

ABSTRACT:
Chemiluminescent substrate delivery systems comprising a conjugate a dendrimer and at least one chemiluminescent substrate are provided. The substrate delivery systems can also include a chemiluminescence enhancer. The dendrimer/chemiluminescent substrate conjugates can be used in kits including an enzyme capable of activating the chemiluminescent substrate to produce a peroxygenated intermediate that decomposes to produce light. The dendrimer/chemiluminescent substrate conjugates can be used in assays to detect the presence of an analyte (e.g., an enzyme, an antibody, an antigen or a nucleic acid) in a sample.

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