Dendritic cell line

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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Details

C435S007220, C435S335000, C435S339000, C435S372000, C435S375000

Reexamination Certificate

active

07341870

ABSTRACT:
The invention relates to plasmacytoid dendritic human cell lines and methods for producing the cell lines. More specifically, the invention relates to the plasmacytoid dendritic human cell line called GEN2.2, which is deposited in the CNCM under number CNCM 1-2938 and the plasmacytoid dendritic human cell line called GEN3, which is deposited in the CNCM under number I-3110. The use of cells from the cell lines is also disclosed.

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patent: 2004/0006032 (2004-01-01), Lopez
patent: WO 02/40646 (2002-05-01), None
patent: WO 02/40647 (2002-05-01), None
Decker WK, Xing D, Shpall EJ. Dendritic cell immunotherapy for the treatment of neoplastic disease. Biol Blood Marrow Transplant. Feb. 20096;12(2):113-25. Review. □□
Laurence Chaperot et al., “Identification of a leukemic counterpart of the plasmacytoid dendritic cells”, 2001 by The American Society of Hematology, Blood, May 15, 2001, vol. 97, No. 10, pp. 3210-3217.
Andrzej Dzionek et al., “Plasmacytoid Dendritic Cells: From Specific Surface Markers to Specific Cellular Functions”, American Society for Histocompatibility and Immunogenetics, 2002 Published by Elsevier Science Inc. Human Immunology 63, pp. 1133-1148 (2002).
Marina Cella et al., “Plasmacytoid monocytes migrate to inflammed lymph nodes and produce large amounts of type I interferon”, Aug. 1999, 919-923, vol. 5, No. 8.
Jacques Banchereau et al., “Immunobiology of Dendritic Cells”, Annu. Rev. Immunol. 2000., 18: pp. 767-811.
Ralph M. Steinman et al., “Exploiting dendritic cells to improve vaccine efficacy”, The Journal of Clinical Investigation, Jun. 2002, vol. 109, No. 12, pp. 1519-1526.

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