Dendritic cell co-stimulatory molecules

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

08053558

ABSTRACT:
A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.

REFERENCES:
patent: 4272398 (1981-06-01), Jaffe
patent: 4376110 (1983-03-01), David et al.
patent: 4650764 (1987-03-01), Temin et al.
patent: 4769330 (1988-09-01), Paoletti et al.
patent: 4861627 (1989-08-01), Mathiowitz et al.
patent: 4861719 (1989-08-01), Miller
patent: 4925673 (1990-05-01), Steiner et al.
patent: 4980289 (1990-12-01), Temin et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5124263 (1992-06-01), Temin et al.
patent: 5155020 (1992-10-01), Paoletti
patent: 5155027 (1992-10-01), Sledziewski et al.
patent: 5175099 (1992-12-01), Wills
patent: 5204243 (1993-04-01), Paoletti
patent: 5225336 (1993-07-01), Paoletti
patent: 5225538 (1993-07-01), Capon et al.
patent: 5240846 (1993-08-01), Collins et al.
patent: 5278056 (1994-01-01), Bank et al.
patent: 5284656 (1994-02-01), Platz et al.
patent: 5451569 (1995-09-01), Wong et al.
patent: 5521288 (1996-05-01), Linsely et al.
patent: 5567584 (1996-10-01), Sledziewski et al.
patent: 5675848 (1997-10-01), Kappel
patent: 5714147 (1998-02-01), Capon et al.
patent: 5750375 (1998-05-01), Sledziewski et al.
patent: 5843725 (1998-12-01), Sledziewski et al.
patent: 5861310 (1999-01-01), Freeman et al.
patent: 5942607 (1999-08-01), Freeman et al.
patent: 6018026 (2000-01-01), Sledziewski et al.
patent: 6291212 (2001-09-01), Sledziewski et al.
patent: 6291646 (2001-09-01), Sledziewski et al.
patent: 6300099 (2001-10-01), Sledziewski et al.
patent: 6323323 (2001-11-01), Sledziewski et al.
patent: 6630575 (2003-10-01), Coyle et al.
patent: 6635750 (2003-10-01), Coyle et al.
patent: 6743619 (2004-06-01), Tang et al.
patent: 6919193 (2005-07-01), Tang et al.
patent: 6965018 (2005-11-01), Mikesell et al.
patent: 7029674 (2006-04-01), Carreno et al.
patent: 7030219 (2006-04-01), Pardoll et al.
patent: 7122351 (2006-10-01), Moore et al.
patent: 7279567 (2007-10-01), Mikesell et al.
patent: 7358354 (2008-04-01), Mikesell et al.
patent: 7368531 (2008-05-01), Rosen et al.
patent: 7381794 (2008-06-01), Moore et al.
patent: 7414122 (2008-08-01), Fox et al.
patent: 7432059 (2008-10-01), Freeman et al.
patent: 7432062 (2008-10-01), Coyle et al.
patent: 7432351 (2008-10-01), Chen
patent: 7560540 (2009-07-01), Pardoll et al.
patent: 7563869 (2009-07-01), Honjo et al.
patent: 7595048 (2009-09-01), Honjo et al.
patent: 7709214 (2010-05-01), Freeman et al.
patent: 7723479 (2010-05-01), Mikesell et al.
patent: 2002/0091246 (2002-07-01), Pardoll et al.
patent: 2002/0095024 (2002-07-01), Mikesell et al.
patent: 2002/0106730 (2002-08-01), Coyle et al.
patent: 2002/0107363 (2002-08-01), Fox et al.
patent: 2002/0110836 (2002-08-01), Freeman et al.
patent: 2002/0164600 (2002-11-01), Freeman et al.
patent: 2003/0142359 (2003-07-01), Bean et al.
patent: 2003/0171551 (2003-09-01), Rosenblatt et al.
patent: 2003/0208058 (2003-11-01), Fiscella et al.
patent: 2003/0232323 (2003-12-01), Freeman et al.
patent: 2004/0010134 (2004-01-01), Rosen et al.
patent: 2005/0228170 (2005-10-01), Fox et al.
patent: 2005/0260716 (2005-11-01), Moore et al.
patent: 2006/0034826 (2006-02-01), Carreno et al.
patent: 2006/0084794 (2006-04-01), Rosen et al.
patent: 2006/0110383 (2006-05-01), Honjo et al.
patent: 2006/0223088 (2006-10-01), Rosen et al.
patent: 2007/0037206 (2007-02-01), Rosen et al.
patent: 2007/0041963 (2007-02-01), Rosen et al.
patent: 2007/0065427 (2007-03-01), Freeman et al.
patent: 2007/0092504 (2007-04-01), Carreno et al.
patent: 2007/0099833 (2007-05-01), Rosen et al.
patent: 2007/0122378 (2007-05-01), Freeman et al.
patent: 2007/0224663 (2007-09-01), Rosen et al.
patent: 2008/0025979 (2008-01-01), Honjo et al.
patent: 2008/0118511 (2008-05-01), Freeman et al.
patent: 2008/0241175 (2008-10-01), Pardoll et al.
patent: 2009/0042292 (2009-02-01), Chen
patent: 2009/0075338 (2009-03-01), Moore et al.
patent: 2009/0269783 (2009-10-01), Coyle et al.
patent: 1074617 (2000-10-01), None
patent: WO 90/07861 (1990-07-01), None
patent: WO 91/10741 (1991-07-01), None
patent: WO 91/17271 (1991-11-01), None
patent: WO 92/00092 (1992-01-01), None
patent: WO 92/01047 (1992-01-01), None
patent: WO 92/20791 (1992-11-01), None
patent: WO93/01222 (1993-01-01), None
patent: WO 95/05464 (1995-02-01), None
patent: WO 95/07707 (1995-03-01), None
patent: WO 97/17613 (1997-05-01), None
patent: WO 97/17614 (1997-05-01), None
patent: WO 97/24447 (1997-07-01), None
patent: WO 98/23635 (1998-06-01), None
patent: WO 98/33914 (1998-08-01), None
patent: WO 99/64597 (1999-12-01), None
patent: WO 00/55375 (2000-09-01), None
patent: WO 00/61612 (2000-10-01), None
patent: WO 01/34629 (2001-05-01), None
patent: WO 01/70979 (2001-09-01), None
patent: WO 01/94413 (2001-12-01), None
patent: WO 02/00692 (2002-01-01), None
patent: WO 02/00730 (2002-01-01), None
patent: WO 02/02587 (2002-01-01), None
patent: WO 02/02587 (2002-01-01), None
patent: WO 02/08279 (2002-01-01), None
patent: WO 02/02891 (2002-03-01), None
patent: WO 02/24891 (2002-03-01), None
patent: WO 02/057453 (2002-07-01), None
patent: WO 02/078731 (2002-10-01), None
patent: WO 02/079474 (2002-10-01), None
patent: WO 02/081731 (2002-10-01), None
patent: WO 03/008583 (2003-01-01), None
patent: WO 2006/050172 (2006-05-01), None
patent: WO 2008/037080 (2008-04-01), None
patent: WO 2009/029342 (2009-03-01), None
patent: WO 2009/114110 (2009-09-01), None
Singh et al., Nature Biotechnology, 1999, 17: 1075-1081.
GenBank Accession No. AF142780, 3 pages (1999).
Sequence alignment, 1 page (2010).
Attwood T., Science, 2000; 290:471-473.
Skolnick et al., Trends in Biotech. 2000; 18(1):34-39.
Gerstmayer, et al., “Costimulation of T cell proliferation by a chimeric B7-2 antibody fusion protein specifically targeted to cells expressing the erbB2 proto-oncogene,”J. Immunol., 158(10): 4584-90 (1997).
Guo, et al., “A novel fusion protein of IP10-scFv retains antibody specificity and chemokine function,”Biochem. Biophys. Res. Commun., 320(2):506-13 (2004).
Lewinski, et al., “Retroviral DNA integration: viral and cellular determinants of target-site selection,”PLoS Pathog., 2(6):e60 (2006).
Lu, et al., “EGF-IL-18 fusion protein as a potential anti-tumor reagent by induction of immune response and apoptosis in cancer cells,”Cancer Lett., 60(1-2):187-97 (2008).
International Search Report for PCT/US01/13430 dated Feb. 20, 2002.
Tseng S. et al., “B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells,”J. Exper. Med., vol. 193, No. 7, (Apr. 2, 2001), pp. 839-845.
Database EM—MUS [Online] EMBL; Accession No. AF142780 (Jun. 1, 1999).
Database EM—HUM [Online] EMBL; Accession No. AK001872 (Feb. 22, 2000).
Chen L. et al., “Costimulation of Antitumor Immunity by the B7 Counterreceptor of the T Lymphocyte Molecules CD28 and CTLA-4,”Cell, vol. 71, (Dec. 24, 1992), pp. 1093-1102.
Gerstmayer B. et al., “Costimulation of T-cell proliferation by a chimeric B7-antibody fusion protein,”Cancer Immunology Immunotherapy, vol. 45, No. 3-4, (Nov. 1997), pp. 156-158.
Henry, J. et al., “Structure and evolution of the extended B7 family,”Immunology Today, vol. 20, No. 6, (Jun. 1999) pp. 285-288.
Yoshinga S.K. et al., “T-cell co-stimulation through B7RP-1 and ICOS,”Naturevol. 402, (Dec. 16, 1999) pp. 827-832.
Townsend S.E. et al, Tumor Rejection After Direct Costimulation of CD8+T Cells by B7-Transfected Melanoma Cells,Science, vol. 259, (Jan. 15, 1993), pp. 368-370.
H. Henry, “Structure and Evolution of the Extended by Family,” vol. 20, Immunology Today, No. 6, Jun. 1999, pp. 285-288.
Gordon J. Freeman, “Cloning

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Dendritic cell co-stimulatory molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dendritic cell co-stimulatory molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dendritic cell co-stimulatory molecules will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4269963

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.