Dendrimeric support or carrier macromolecule

Details Dendrimeric support or carrier macromolecule Dendrimeric support or carrier macromolecule

2006-08-29

2006-08-29

Riley, Jezia (Department: 1637)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

C514S772000, C549S370000, C528S272000, C536S023100

Reexamination Certificate

active

07097856

ABSTRACT:
The present invention provides a family of dendrimers that are useful as supports, vectors, carriers or delivery vehicles for a variety of compounds in biomedical and technological applications. In particular, the macromolecules may be used for the delivery of drugs, genetic material, imaging components or other functional molecule to which they can be conjugated. An additional feature of the macromolecules is their ability to be targeted for certain organs, tumors, or types of tissues.

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Annby, U. et al., “Benzylidene Protected Bis-MPA, A Convenient Dendrimer Building Block,”Tetrahedron Letters, Elsevier Science Publishers, Amsterdam, NL, 39:3217-3220 (1998).
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Trollsas, M. et al., “Versatile and Controlled Synthesis of Star and Branched Macromolecules by Dendrimeric Initiation,”Macromolecules, 30:8508-8511 (1997).

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