Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1994-11-28
1998-12-15
Walsh, Stephen
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530300, 530402, 530839, 530 10, C07K 14705
Patent
active
058498699
ABSTRACT:
The present invention relates to nucleotide sequences of the Delta genes, and amino acid sequence of the encoded protein, fragments and derivatives which retain binding activity are also provided.
REFERENCES:
patent: 3884853 (1975-05-01), Zimmerman
patent: 5098833 (1992-03-01), Laiky
patent: 5115096 (1992-05-01), Shoyab et al.
patent: 5368712 (1994-11-01), Tomich et al.
patent: 5580738 (1996-12-01), Laborda
Fleming et al., 1990, "The gene Serate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster," Genes & Dev., 4(12A):2188-2201.
Bass et al., 1991, Proc. Natl. Acad. Sci., USA. 88:4498-4502.
Arthos et al., 1989, Cell. 57:469-481.
Ashkenazi et al., 1990, Proc. Natl. Acad. Sci., USA 87:7150-7154.
Artavanis-Tsakonas et al., 1991, "The notch locus and the cell biology of neuroblast segregation," Ann. Rev. Cell. Biol., 7:427-452.
Digan et al., 1989, "Continuous production of a novel lysozyme via secretion from the yeast, pichia pastoris," Bio/technology, 7:160-164.
Evan et al., 1985, "Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product," Mol. Cell. Biol., 5(12):3610-3616.
Field et al., 1988, "Purification of a RAS-responsive adenylyl cyclase cmplex from Saccharomyces cerevisiaeby use of an epitope addition method," Mol. Cell. Biol., 8(5):2159-2165.
Hopp et al., 1988, "A short polypeptide marker sequence useful for recombinant protein identification and purification, " Bio/technology, 6:1204-1210.
Parks and Muskavitch, 1993, "Delta function is required for bristle organ determination and morphogenesis in Drosophila," Dev. Biol. 157:484-496.
Weinmaster et al., 1992, "Notch2: a second mammalian notch gene," Develop., 116:931-941.
Artavanis-Tsokonas et al., 1983, "Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster," Proc. Natl. Acad. Sci., USA, 80:1977-1981.
Doolitle, 1987, OF URFS AND ORFS, A Primer on How to Analyze Derived Amino Acid Sequences, University Science books, Mill Valley, California, pp. 10-17 and 63-79.
Hopp and Woods, 1981, "Prediction of protein antigenic determinants from amino acid sequences," Proc. Natl. Acad. Sci., USA, 78:3824-3828.
Rebay et al., 1991, "Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor," Cell. 67:687-699.
Stifani et al., 1992, "Human homologs of a Drosophila Enhances of split gene product define a novel family of nuclear proteins," Nature 2:119-127.
Ohno et al., 1990, "The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control," Cell. 60:991-997.
Dahlback et al., 1990, "Novel type of very high affinity calcium binding sites in .beta.-hydroxy-asparagine-containing epidermal growth factor-like domains in vitamin K-dependent protein S," J. Biol. Chem., 265:18481-18489.
LaMarco et al., 1991, "Identification of Ets-and Notch related subunits in GA binding protein," Science, 253:789-792.
Adams et al., 1991, "Complementary DNA sequencing: expressed sequence tags and human genome project," Science. 252:1651-1656.
Kramer et al., 1991, "Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine kinase receptor," Nature, 352:207-212.
Welshons, 1965, Science 150:1122-1129.
Portin, 1975, Genetics 81:121-133.
Morita et al., 1984, J. Biol. Chem. 259:5698-5704.
Sugo et al., 1984, J. Biol. Chem. 259:5705-5710.
Lindsley and Zinn, 1985, Drosophila Information Service 62:86.
Sudhof et al. 1985, Science 228:815-822.
Doe and Goodman, 1985, Dev. Biol. 111:206-219.
Vassin et al., 1985, J. Neurogenet. 2:291-308.
Wharton et al., 1985, Cell. 43:567-581.
Kidd et al., 1986, Mol. Cell. Biol. 6:3094-3108.
Breeden and Nasmyth, 1987, Nature 329:651-654.
Appella et al., 1987, J. Biol. Chem., 262:4437-4440.
Knust et al., 1987, EMBO J. 6(3):761-766.
Suzuki et al., 1987, EMBO J. 6(7):1891-1897.
Hartley et al., 1987, EMBO J. 6(11):3407-3417.
Reynolds et al., 1987, Cell 50:107-117.
Vassin et al., 1987, EMBO J. 6:3431-3440.
Kelly et al., 1987, Cell 51:539-548.
Kopczynski et al., 1988, Genes & Dev. 2: 1723-1735.
Kopczynski and Muskavitch, 1989, Development 107:623-636.
Rees et al., 1988, EMBO J. 7(7):2053-2061.
Furie and Furie, 1988, Cell 53:505-518.
Artavanis-Tsakonas, 1988, Trends in Genetics 4:95-100.
Kurosawa et al., 1988, J. Biol. Chem. 263(13):5993-5996.
Yochem et al., 1988, Nature 335:547-550.
Rothberg et al., 1988, Cell 55:1047-1059.
Kidd et al., 1989, Genes & Dev. 3:1113-1129.
Johansen et al., 1989, J. Cell Biol. 109:2427-2440.
Shepard et al., 1989, Genetics 122:429-438.
Alton et al., 1989, Dev. Genet. 10:261-272.
Handford et al., 1990, EMBO J. 9:475-480.
Fehon et al., 1990, Cell 61:523-534.
Coffman et al., 1990, Science 249:1438-1441.
Palka et al., 1990, Develop. 109:167-175.
Xu et al., 1990, Genes & Dev. 4:464-475.
Ellisen et al., 1991, Cell 66:649-661.
Weinmaster et al., 1991, Develop. 113:100-205.
Kopczynski et al., "Molecular and Genetic Intimations of the Functions of Delta...", Mol. Reprod. Devel. 27(1):28-36. (Sep. 1990).
Hjelmeland et al., "Solubilization of Functional Membrane Proteins", Meth. Enzymol. 104(Part C): 305-318 (1984).
Haenlin et al., Develop. 110:905-914 (Nov. 1990).
Artavanis-Tsakonas Spyridon
Fehon Richard Grant
Muskavitch Marc Alan-Telander
Shephard Scott Brockwell
Indiana University Foundation
Sorensen Kenneth A.
Walsh Stephen
Yale University
LandOfFree
Delta fragments and derivatives and methods based thereon does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Delta fragments and derivatives and methods based thereon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Delta fragments and derivatives and methods based thereon will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1459035