.DELTA.8- and .DELTA.9-prostaglandin derivatives, process for th

Details .DELTA.8- and .DELTA.9-prostaglandin derivatives, process for th .DELTA.8- and .DELTA.9-prostaglandin derivatives, process for th

1992-11-25

1994-12-27

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514570, 548237, 549371, 560 60, 560 61, 562470, 562471, C07C40500, A61K 31557

Patent

active

053766830

ABSTRACT:
The invention relates to .DELTA..sup.8 - and .DELTA..sup.9 -prostaglandin derivatives of formula I, ##STR1## in which means the radicals or , R.sup.1 means ##STR2## COOR.sup.4 or CONHR.sup.5, R.sup.2 and R.sup.3 respectively mean a hydrogen atom or a hydroxy group, and the OH group can be respectively in alpha- or beta- position,

REFERENCES:
Olah, George A. et al., "Synthetic Methods and Reactions IX.sup.1 Fluorination of Secondary- and Tertiary-Alcohols with Polyhydrogen Fluoride/Pyridine (Trialkylamine) Reagents."
J. of American Chem. Society Feb. 6, 1974, "Synthetic Methods and Reactions . . . " pp. 925-927.
Green, Chem Comm 611 (1977).
Somekh, JOC. 48 907 (1983).

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