.DELTA.4-Steroid compounds and a process for their production

Details .DELTA.4-Steroid compounds and a process for their production .DELTA.4-Steroid compounds and a process for their production

1982-08-13

1984-05-15

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603973, 26039745, C07J 900

Patent

active

044487258

ABSTRACT:
New .DELTA.4-steroid compounds optionally containing a further double bond in the 1-position and an 11-oxygen function and corresponding to general formula I below: ##STR1## in which X represents halogen, particularly chlorine or bromine, or NH.sub.2 and Y is a hydroxyl group, or together with the C-atom substituted by Y, represents a carbonyl group, are obtained from the associated steroid-20-carboxylic acids by reaction with a halogenating agent in substantially stoichiometric quantities at temperatures not exceeding 15.degree. C., after which the steroid-20-carboxylic acid halide formed is, if desired, reacted with ammonia or with a compound which yields ammonia.

REFERENCES:
patent: 2752369 (1956-06-01), Holysz et al.
patent: 3539687 (1970-11-01), Kuhnen et al.
patent: 4255345 (1981-03-01), Krbechek

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