Delivery system for enhanced onset and increased potency

Details Delivery system for enhanced onset and increased potency Delivery system for enhanced onset and increased potency

1992-06-29

1995-06-13

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424464, 424461, 424462, 424468, A61K 920

Patent

active

054240751

ABSTRACT:
The invention discloses a swallow tablet which is capable of disintegrating within less than about fifteen minutes and providing fast delivery of therapeutic drugs. The delivery system is composed of between 0.250 and 1.0 Gm of an alkali metal or alkaline-earth metal salt of an edible organic acid. A preferred delivery system is trisodium citrate.

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patent: 3865935 (1975-02-01), Amann
patent: 4824664 (1989-04-01), Tarral et al.
patent: 4861592 (1989-08-01), Gottwald et al.
patent: 5064656 (1991-11-01), Gergely et al.
patent: 5069910 (1991-12-01), Kovacic et al.
patent: 5137730 (1992-08-01), Dennis et al.
Remingtons Pharmaceutical Sciences, Mack Publishing, Co. 18th Edition, 1990.
S. Ojantakanen ACT A Pharmaceutica Fennica 99, 1990, 119-126.
Remington Pharmaceutical Sciences Mak Publishing Co., 18th Edition, 1990.
Acta Pharmaceutical Fennica 1990: 99, 119-126 "Bioavailability of Ibuprofen from Hard Gelatin Capsules . . . " S. Ojantakanen et al.

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