Surgery – Controlled release therapeutic device or system
Patent
1984-10-18
1986-09-23
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
604893, A61M 500
Patent
active
046133305
ABSTRACT:
A system for the controlled delivery of a desired agent to a fluid environment. A semipermeable container defines a fully enclosed cavity and is imperforate except for a plurality of pores for permitting fluid to flow from the fluid environment into the cavity. A quantity of a molecular complex is positioned in the cavity. The molecular complex comprises a macromolecule that is non-diffusable with respect to the container and a desired agent complexed to the macromolecule, the agent being capable of dissociating from the macromolecule over time. The pores of the container have a larger size in relation to the agent and the container is so constructed as to permit unimpeded passage of the agent through the pores. The concentration of the agent within the cavity is controlled by the equilibrium between the molecular complex and the agent within the cavity and the active agent is deliverable by the system to the fluid environment exclusively through the plurality of pores.
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Rosenbaum C. Fred
Vinyard Sherri
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