Delivery system for dental agents

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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Details

424 49, A61K 716, A61K 718

Patent

active

061398209

ABSTRACT:
Toothpaste and other dentifrices formulated to include a volume increasing agent (density reducing agent) in order to significantly increase the volume of the toothpaste at the time it is dispensed onto a toothbrush. The inventive dental compositions preferably include a substantial quantity of entrained or trapped air or other gas in order to reduce the density, and hence the weight, of toothpaste actually placed within a person's mouth. The result is a reduction in the amount of active ingredients introduced into a person's mouth that might be ingested. The entrained air or other gas can also increase the availability of the active ingredient since the foamed composition increases the dispersibility of the active ingredients within saliva. The net effect is that a person decreases the actual amount of toothpaste without decreasing the volume, or visual amount, of toothpaste dispensed on the toothbrush. The density-reduction effect can alternatively be provided by means of a lower density filler in addition to, or instead of, the entrained gas. Such fillers typically include trapped air or voids.

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