Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1994-04-05
1996-08-13
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 514 2, 514 21, 530300, 530353, 530840, 623 14, A61F 228, A61K 3839, C07K 14485, C07K 1451
Patent
active
055454097
ABSTRACT:
A composition and method for controlled release of water-soluble proteins comprising a surface-eroding polymer matrix and water-soluble bioactive factors is described. The composition bioerodes in the biological environment of the subject at a controlled rate, thereby releasing the water soluble proteins at a rate which allows them to interact with local cell populations.
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Domb Abraham
Glowacki Julianne
Langer Robert S.
Laurencin Cato T.
Lucas Paul A.
Azpuru Carlos
Massachusetts Institute of Technology
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