Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Miscellaneous
Patent
1992-04-29
1995-08-22
Isabella, David
Prosthesis (i.e., artificial body members), parts thereof, or ai
Miscellaneous
A61F 202
Patent
active
054435315
ABSTRACT:
A method of preparing a delivery system for a biologically active growth and morphogenetic factor by using chromatographic techniques and which includes introducing such biologically active factor into a chromatography column of appropriate dimensions which contains a porous carrier comprising a solid adsorbent selected for its specific affinity for such biologically active factor. In one embodiment of the invention porous hydroxyapatite is used as the carrier for bone morphogenetic proteins (ie BMPs). The invention extends to a delivery system prepared according to the above method; to an apparatus for preparing the delivery system according to the method; and to use of the delivery system in a method for inducing the formation of new bone in primates.
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U.S. patent application Ser. No. 07/720,174 filed Jun. 27, 1991 to U. Ripamonti.
Isabella David
South African Medical Research Council
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