Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2004-08-04
2010-02-09
Ton, Thaian N. (Department: 1632)
Chemistry: molecular biology and microbiology
Vector, per se
C424S093200
Reexamination Certificate
active
07659113
ABSTRACT:
A retroviral delivery system capable of transducing a target site is described. The retroviral delivery system comprises a first nucleotide sequence coding for at least a part of an envelope protein; a second nucleotide sequence coding for at least a part of an envelope protein and one or more other nucleotide sequences derivable from a retrovirus that ensure transduction of the target site by the retroviral delivery system; wherein the first and second nucleotide sequences are heterologous with respect to at least one of the other nucleotide sequences; and wherein the first nucleotide sequence codes for at least a part of an influenza HA protein or a mutant, variant, derivative or fragment thereof that is capable of recognising the target site. Preferably said second protein is an influenza M2 protein.
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Frommer & Lawrence & Haug LLP
Garman Russell A.
Kowalski Thomas J.
Shen Wu-Cheng Winston
Ton Thai-an N.
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