Delivery of therapeutic agents to a target site

Details Delivery of therapeutic agents to a target site Delivery of therapeutic agents to a target site

1994-11-08

1996-02-13

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424 49, 4241341, 4241501, 4241641, 4241651, A61K 716, A61K 920, A61K 3900

Patent

active

054909880

ABSTRACT:
An antibody fragment able to bind to a target site is prolonged by an additional peptide. The Therapeutic agent is bound to this peptide or means are provided to bring about such binding. The antibody fragment and possibly also the therapeutic agent are included in a product so that binding to the target site delivers the therapeutic agent to the vicinity. The product may for example be for dental care, such as a toothpaste or mouthwash and the antibody fragment may then bind to a component of dental plaque.

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Oranei et al, Proc. Natl. Acad. Sci. USA 86 3833 (1989).
John Hodgson in Biotechnology, vol. 9, p. 422 (May 1991).
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