Delivery of sedative-hypnotics through an inhalation route

Details Delivery of sedative-hypnotics through an inhalation route Delivery of sedative-hypnotics through an inhalation route

2006-08-07

2008-11-04

Haghighatian, Mina (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S434000, C424S489000, C424S499000, C514S958000, C128S200140, C128S200150, C128S200240

Reexamination Certificate

active

07445768

ABSTRACT:
The present invention relates to the delivery of sedative-hypnotics through an inhalation route. Specifically, it relates to aerosols containing sedative-hypnotics that are used in inhalation therapy. In a method aspect of the present invention, a sedative-hypnotic drug is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of a sedative-hypnotic, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% sedative-hypnotic drug degradation products. In a kit aspect of the present invention, a kit for delivering a sedative-hypnotic through an inhalation route is provided which comprises: a) a thin layer of a sedative-hypnotic drug and b) a device for dispensing said thin layer a sedative-hypnotic drug as a condensation aerosol.

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