Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Reexamination Certificate
2006-03-14
2006-03-14
Padmanabhan, Sreeni (Department: 1616)
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
C424S046000, C424S489000, C424S499000, C128S200140, C128S200240, C514S958000
Reexamination Certificate
active
07011819
ABSTRACT:
The present invention relates to the delivery of headache and anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing that are used in inhalation therapy. In a method aspect of the present invention, rizatriptan or zolmitriptan is administered to a patient through an inhalation route. The method comprises: a) heating a composition, comprising rizatriptan or zolmitriptan to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol with less than 5% of the drug degradation products. In a kit aspect of the present invention, a kit for delivering rizatriptan or zolmitriptan through an inhalation route is provided which comprises: a) a thin coating of a rizatriptan or zolmitriptan composition; and, b) a device for dispending said thin coating as a condensation aerosol.
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patent: W
Hale Ron L.
Rabinowitz Joshua D.
Solas Dennis W.
Zaffaroni Alejandro C.
Alexza Pharmaceuticals, Inc.
Haghighatian Mira
Leschensky William L.
Padmanabhan Sreeni
Swanson & Bratschun LLC
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