Delivery of multiple doses of medications

Details Delivery of multiple doses of medications Delivery of multiple doses of medications

2003-06-10

2008-10-07

Sheikh, Humera N. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S451000, C424S458000, C424S462000, C424S464000, C424S468000, C424S474000, C424S480000, C424S489000, C424S490000

Reexamination Certificate

active

07431944

ABSTRACT:
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more additional doses at predetermined times. By providing such a drug release profile, the dosage forms eliminate the need for a patient to carry an additional dose for ingestion during the day. The dosage forms and methods provided are useful in administering methylphenidate and pharmaceutically acceptable salts thereof, which generally require one or more doses throughout the day.

REFERENCES:
patent: 2507631 (1950-05-01), Hartmann et al.
patent: 2838519 (1958-06-01), Rometsch et al.
patent: 2957880 (1960-10-01), Rometsch
patent: 4137300 (1979-01-01), Sheth et al.
patent: 4410700 (1983-10-01), Rice
patent: 4794001 (1988-12-01), Mehta et al.
patent: 4882166 (1989-11-01), Graham et al.
patent: 4904476 (1990-02-01), Mehta et al.
patent: 4968505 (1990-11-01), Okada et al.
patent: 4986987 (1991-01-01), Ayer et al.
patent: 4992445 (1991-02-01), Lawter et al.
patent: 5104899 (1992-04-01), Young et al.
patent: 5114946 (1992-05-01), Lawter et al.
patent: 5133974 (1992-07-01), Paradissis et al.
patent: 5137733 (1992-08-01), Noda et al.
patent: 5156850 (1992-10-01), Wong et al.
patent: 5158777 (1992-10-01), Abramowitz et al.
patent: 5160744 (1992-11-01), Jao et al.
patent: 5202128 (1993-04-01), Morella et al.
patent: 5217718 (1993-06-01), Colley et al.
patent: 5223265 (1993-06-01), Wong
patent: 5229131 (1993-07-01), Amidon et al.
patent: 5232705 (1993-08-01), Wong et al.
patent: 5236689 (1993-08-01), Wong et al.
patent: 5283193 (1994-02-01), Yamamoto et al.
patent: 5284769 (1994-02-01), Evans et al.
patent: 5299121 (1994-03-01), Brill et al.
patent: 5308348 (1994-05-01), Balaban et al.
patent: 5326570 (1994-07-01), Rudnic et al.
patent: 5331000 (1994-07-01), Young et al.
patent: 5362755 (1994-11-01), Barberich et al.
patent: 5375693 (1994-12-01), Woosley et al.
patent: 5391381 (1995-02-01), Wong et al.
patent: 5425950 (1995-06-01), Dandiker et al.
patent: 5449743 (1995-09-01), Kobayashi et al.
patent: 5478573 (1995-12-01), Eichel et al.
patent: 5496561 (1996-03-01), Okada et al.
patent: 5500227 (1996-03-01), Oshlack et al.
patent: 5512293 (1996-04-01), Landrau et al.
patent: 5567441 (1996-10-01), Chen
patent: 5580578 (1996-12-01), Oshlack et al.
patent: 5593694 (1997-01-01), Hayashida et al.
patent: 5639476 (1997-06-01), Oshlack et al.
patent: 5672360 (1997-09-01), Sackler et al.
patent: 5733756 (1998-03-01), Zeitlin et al.
patent: 5773478 (1998-06-01), Richards et al.
patent: 5837284 (1998-11-01), Mehta et al.
patent: 5874090 (1999-02-01), Baker et al.
patent: 5908850 (1999-06-01), Zeitlin et al.
patent: 5922736 (1999-07-01), Dariani et al.
patent: 5936091 (1999-08-01), Khetani et al.
patent: 5965734 (1999-10-01), Ramaswamy et al.
patent: 6031124 (2000-02-01), Fox et al.
patent: 6113879 (2000-09-01), Richards et al.
patent: 6121453 (2000-09-01), Zavareh
patent: 6127385 (2000-10-01), Midha et al.
patent: 6217904 (2001-04-01), Midha et al.
patent: 6221883 (2001-04-01), Baldessarini et al.
patent: 6228398 (2001-05-01), Devane et al.
patent: 6242464 (2001-06-01), Harris et al.
patent: 6255325 (2001-07-01), Dariani et al.
patent: 6344215 (2002-02-01), Bettman et al.
patent: 6355656 (2002-03-01), Zeitlin et al.
patent: 6359139 (2002-03-01), Khetani et al.
patent: 6395752 (2002-05-01), Midha et al.
patent: 6441178 (2002-08-01), Zavareh et al.
patent: 6468504 (2002-10-01), Richards et al.
patent: 6486177 (2002-11-01), Zeldis et al.
patent: 6528530 (2003-03-01), Zeitlin et al.
patent: 6531489 (2003-03-01), Harris et al.
patent: 6602887 (2003-08-01), Dariani et al.
patent: 6635284 (2003-10-01), Mehta et al.
patent: 6730325 (2004-05-01), Devane et al.
patent: 6962997 (2005-11-01), Khetani et al.
patent: 7115631 (2006-10-01), Zeldis et al.
patent: 2002/0019535 (2002-02-01), Zavareh et al.
patent: 2002/0032335 (2002-03-01), Langston et al.
patent: 2002/0103162 (2002-08-01), Epstein et al.
patent: 2002/0132793 (2002-09-01), Epstein et al.
patent: 2003/0049205 (2003-03-01), Richards et al.
patent: 2003/0105134 (2003-06-01), Harris et al.
patent: 2003/0170181 (2003-09-01), Midha
patent: 1297368 (1992-03-01), None
patent: 2 368 367 (2000-10-01), None
patent: 2 376 215 (2001-12-01), None
patent: 2 223 643 (2003-12-01), None
patent: 0 636 366 (1995-02-01), None
patent: 0 885 191 (2002-01-01), None
patent: 0 889 874 (2002-01-01), None
patent: 0 841 928 (2002-09-01), None
patent: 0 879 228 (2002-10-01), None
patent: 0 958 281 (2004-03-01), None
patent: 2 635 460 (1994-09-01), None
patent: 589625 (1945-01-01), None
patent: 788226 (1957-12-01), None
patent: 878167 (1961-09-01), None
patent: 466229 (1975-04-01), None
patent: WO93/05769 (1993-01-01), None
patent: 96/41617 (1996-12-01), None
patent: WO97/03671 (1997-02-01), None
patent: WO97/03672 (1997-02-01), None
patent: WO97/03673 (1997-02-01), None
patent: WO97/27176 (1997-07-01), None
patent: WO97/28124 (1997-08-01), None
patent: WO97/32851 (1997-09-01), None
patent: WO97/35836 (1997-10-01), None
patent: WO98/06380 (1998-02-01), None
patent: WO98/23263 (1998-04-01), None
patent: WO98/25902 (1998-06-01), None
patent: WO98/31668 (1998-07-01), None
patent: WO98/14168 (1998-09-01), None
patent: WO99/62496 (1999-12-01), None
patent: WO 00/74680 (2000-12-01), None
patent: WO 01/43730 (2001-06-01), None
patent: 2004/026258 (2004-04-01), None
Aoyama, T. et al., “Pharmacodynamic Modeling for Change of Locomotor Activity by Methyllphenidate in Rats,”Pharmaceutical Research,1997, 14(11), 1601-1606.
Aoyama, T. et al., “Pharmacokinetics and pharmacodynamics of methylphenidate enantiomers in rats,”Psychopharmacology,1996, 127, 117-122.
Aoyama, T., et al., “Nonlinear kinetics of threo-methylphenidate enantiomers in a patient with narcolepsy and in healthy volunteers,”Eur. J. Clin. Pharmacol.,1993, 44, 79-84.
Barkley, R. A., et al., “The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study,”J. Am. Acad. Adolesc. Psychiatry.,1990, 29(4), 546-557.
Baughman, Jr., F. A., “Treatment of Attention-Deficit/Hyperactivity Disorder,”JAMA.,Apr. 28, 1999, 218(16), 1490-1491.
Bruera, E., and Neumann, C. M., “The uses of psychotropics in symptom management in advanced cancer,”Pscyho-Oncology.,1998, 7, 346-358.
Carey, W. B., “What the multimodal treatment study of children with attention-deficit/hyperactivity disorder did and did not say about the use of methylphenidate for attention deficits,”Pediatrics,2000, 863-864.
Coyle, J. T., “Psychotic drug use in very young children,”J. Am. Med. Assn.,2000, 283(8), 1059-1060.
Davids, E. et al., “Stereoselective effects of methylphenidate on motor hyperactivity in juvenile rats induced by neonatal 6-hydroxydopamine lesioning,”Psychopharmacology,2002, 160, 92-98.
Ding, Y.-S. et al., “Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo andl-threo-methylphenidate in the human and baboon brain,”Psychopharmacology,1997, 131, 71-78.
Ding, Y.-S. et al., “Is the L-threo Enantiomer of Methylphenidate (Ritalin) Inactive in the Brain when the Drug is Given Orally?”ACNP 41stAnnual Meeting,Dec. 8-12, 2002, Scientific Abstract No. 119.
Garland, E. J., “Pharmacotherapy of adolescent attention deficit hyperactivity disorder: challenges, choices and caveats,”J. Psychopharmacology.,1998, 12(4), 385-395.
Golden, G. S., “Role of attention deficit hyperactivity disorder in learning disabilities,”Seminars in Neurology.,1991, 11(1), 35-41.
Goldman, L. S., et al., “Diagnosis and treatment of attention-deficit/hyperactivity disorder in children and adolescents,”J. Am. Med. Assn.,1998, 279(14), 1100-1107.
Jadad, A. R., et al., “Review: Pharmacologic interventions are more effective than non-pharmacologic for attention-deficit hyperactivity disorder,”Therapeutics, ACP Journal Club.,Nov./Dec. 2000, 110.
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