Delivery of exogenous DNA sequences in a mammal

Details Delivery of exogenous DNA sequences in a mammal Delivery of exogenous DNA sequences in a mammal

1994-03-18

1996-12-03

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435 691, 4351723, A01N 4304, A61K 3170, C12P 2106, C12N 1500

Patent

active

055808590

ABSTRACT:
Polynucleotide sequences, comprising DNA and RNA molecules can be directly administered, for example by injection, to tissues, such as muscle, and expressed as a protein, polypeptide or polypeptide. The polynucleotides can be contained within liposomes or the polynucleotides can free from association with transfection-facilitating proteins, viral particles, liposomal formulations, charged lipids and calcium phosphate precipitating agents.

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