Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-02-16
1998-09-22
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424 851, 424465, 424474, 424475, 424479, 424481, 424485, 424488, 514 3, 514 12, 514 21, 514177, 514178, 514179, 514180, 514181, 514182, 514777, 514780, 514782, 514960, 514961, A61K 924, A61K 934, A61K 936, A61K 3800
Patent
active
058113886
ABSTRACT:
Pharmaceutical compositions for orally delivering a therapeutically effective amount of a drug to the colon without significant release of the drug in the upper GI tract after oral administration of the composition are described. The composition is a unit dosage in the form of a tablet that comprises about 0.01% by weight to about 10% by weight of the drug that is useful in treating a colonic disorder or that is absorbed from the colon; about 40% by weight to about 98% by weight of a hydrocolloid gum obtainable from higher plants; and about 2% by weight to about 50% by weight of a pharmaceutically acceptable binder. The compositions are useful for treating lower GI disorders in human subjects by administering a suitable amount to a subject in need thereof. A particularly preferred aspect is the process for preparing such composition in the form of a tablet.
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Friend David R.
Wong David
Cibus Pharmaceutical, Inc.
Russel Jeffrey E.
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