Delivery of drugs to the lower gastrointestinal tract

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424451, 424456, 424463, 424464, 424469, 424474, 424475, 424479, 424482, A61K 926, A61K 930, A61K 948, A61K 952

Patent

active

058493271

ABSTRACT:
Diseases of the colon are treated by oral ingestion of a unit dosage form containing a plurality of porous microscopic beads, the pores containing an active agent or drug and plugged with a polysaccharide that is chemically degradable by colon-specific bacteria. The dosage form further contains a coating of an enteric material that remains intact until the dosage form reaches the colon.

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