Delivery of diazepam through an inhalation route

Details Delivery of diazepam through an inhalation route Delivery of diazepam through an inhalation route

2006-08-07

2008-12-30

Haghighatian, Mina (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S489000, C424S434000, C424S499000, C514S958000, C128S200140, C128S200240, C128S203150

Reexamination Certificate

active

07470421

ABSTRACT:
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols containing diazepam that are used in inhalation therapy. In a method aspect of the present invention, diazepam is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of diazepam on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering diazepam through an inhalation route is provided which comprises: a) a thin coating of a diazepam composition; and, b) a device for dispending said thin coating as a condensation aerosol.

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