Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Reexamination Certificate
2006-08-08
2006-08-08
Padmanabhan, Sreenivasan (Department: 1616)
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
C424S046000, C424S489000, C424S499000, C514S958000, C128S200140, C128S200240, C128S203150
Reexamination Certificate
active
07087218
ABSTRACT:
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols containing diazepam that are used in inhalation therapy. In a method aspect of the present invention, diazepam is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of diazepam on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering diazepam through an inhalation route is provided which comprises: a) a thin coating of a diazepam composition; and, b) a device for dispending said thin coating as a condensation aerosol.
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Rabinowitz Joshua D.
Zaffaroni Alejandro C.
Alexza Pharmaceuticals, Inc.
Haghighatian Mina
Leschensky William L.
Padmanabhan Sreenivasan
Swanson & Bratschun LLC
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