Delivery of alprazolam, estazolam, midazolam or triazolam...

Details Delivery of alprazolam, estazolam, midazolam or triazolam... Delivery of alprazolam, estazolam, midazolam or triazolam...

2006-06-13

2008-11-11

Haghighatian, Mina (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S434000, C424S489000, C424S499000, C514S958000, C128S200140, C128S200240, C128S200150

Reexamination Certificate

active

07449173

ABSTRACT:
The present invention relates to aerosols containing alprazolam, estazolam, midazolam or triazolam that are used in inhalation therapy. In a method aspect of the present invention, alprazolam, estazolam, midazolam or triazolam is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of alprazolam, estazolam, midazolam or triazolam, on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering alprazolam, estazolam, midazolam or triazolam through an inhalation route is provided which comprises: a) a thin coating of an alprazolam, estazolam, midazolam, or triazolam composition and b) a device for dispensing said thin coating as a condensation aerosol.

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