Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1991-07-23
1994-07-19
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424422, 424441, 424485, 424488, A61K 914
Patent
active
053307631
ABSTRACT:
A method is disclosed for preparing pharmaceutical and other matrix systems that comprises solidifying a matrix composition dissolved or dispersed in a first solvent and subsequently contacting the solidified matrix with a second solvent that is substantially miscible with the first solvent at a temperature lower than the solidification point of the first solvent, the matrix components being substantially insoluble in the second solvent, whereby the first solvent is substantially removed resulting in a usable matrix.
REFERENCES:
patent: 4946684 (1990-08-01), Blank et al.
patent: 5039540 (1991-08-01), Ecanow
patent: 5079018 (1992-01-01), Ecanow
Carbone James
Davies J. Desmond
Gole Dilip J.
Levinson R. Saul
Benston William E.
Janssen Pharmaceutica Inc.
Page Thurman K.
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