Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system
Patent
1994-12-07
1995-10-10
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
Osmotic or diffusion pumped device or system
6048901, 604143, 424422, A61K 922
Patent
active
054566797
ABSTRACT:
Delivery devices which include a beneficial agent and an activating mechanism in separate compartments separated by a moveable partition are designed to deliver the beneficial agent in a pulsatile manner through an orifice. The pulsatile delivery is achieved by a band of resilient material which is placed over the orifice. The resilient material is sufficiently tight to substantially seal the orifice when the pressure within the device is below a threshold level while at the same time being capable of being stretched when the internal pressure exceeds the threshold.
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Baile Clifton A.
Balaban Stephen M.
Pike James B.
Smith Jonathan P.
ALZA Corporation
Ito Richard T.
Mandell Edward L.
Rosenbaum C. Fred
Smith Chalin
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