Delayed release pharmaceutical preparations

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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A61K 922

Patent

active

040137848

ABSTRACT:
A novel delayed release pharmaceutical preparation which is free of added enzymes and thus is stable on storage is provided. The preparation comprises particles of the therapeutically effective agent, a water-soluble calcium salt, and, if desired, a filler material, stabilizer, and other additives uniformly embedded in a triglyceride of fatty acids with 12 to 18 carbon atoms, thereby forming a granular preparation of a grain size between about 0.1 mm. and about 1.0 mm. A process of producing such a preparation is also disclosed.

REFERENCES:
patent: 2793979 (1957-05-01), Svedres
patent: 2805977 (1957-09-01), Robinson et al.
patent: 2875130 (1959-02-01), Grass et al.
patent: 2987445 (1961-06-01), Levesque
patent: 3062720 (1962-11-01), Costello
patent: 3146167 (1964-08-01), Lantz et al.
patent: 3400197 (1968-09-01), Lippmann
patent: 3629393 (1971-12-01), Nakamoto et al.
C.A. 79 No. 27063r (1973).
C.A. 78 No. 47805s (1973); C.A. 73 No. 38547d (1970); C.A. 75 No. 674766 (1971).
C.A. 76 No. 37436s (1972); C.A. 60 No. 15686n (1964); C.A. 68 No. 11496w (1968); C.A. 76 No. 68234d (1972).
C.A. 77 No. 147956g (1972).

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