Delayed release coated tablet of bupropion hydrochloride

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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Details

424468, 424480, A61K 932, A61K 936, A61K 922, A61K 31135

Patent

active

061433276

ABSTRACT:
The invention provides a delayed release coated tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a lubricant; and (ii) a first coating consisting essentially of a water-insoluble, water-permeable film-forming polymer, a plasticizer and a water-soluble polymer; and (iii) a second coating consisting essentially of a methacrylic polymer and a plasticizer therefor.

REFERENCES:
patent: 4687660 (1987-08-01), Baker et al.
patent: 4716041 (1987-12-01), Kjornaes et al.
patent: 4769027 (1988-09-01), Baker et al.
patent: 5427798 (1995-06-01), Ludwig et al.
patent: 5681584 (1997-10-01), Savastano et al.

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